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Application note·Jul 2025

Amperometric measurement of blood glucose test strips

Amperometric measurement of blood glucose test strips

The majority of electrochemical sensors work by measuring Faradaic reactions caused by redox specimens on the electrode–solution interface. Measurements can be conducted either in steady-state mode or non-steady-state mode.

In a steady-state measurement the electrode is held at a constant voltage or current, and the corresponding signal is measured. In a non-steady-state measurement, the voltage or current is swept and the system response is recorded.

In this application note we reproduce the readout of a commercial blood glucose strip using the ECA-5M and disposable enzymatic strips. The chronoamperometric step is applied for a few seconds and the resulting current is integrated to obtain a glucose concentration estimate.

Results across the calibration range agree closely with the reference glucometer, demonstrating that the ECA-5M can serve as a research-grade replacement for fixed-purpose readers, with full control over waveform, sampling, and data export.